Practice Problems for Organic Chemistry by David R. Klein

Studying organic chemistry with Klein? The table below maps every chapter of the 4th edition (Wiley, 2021) to matching free practice on RealOChem — interactive problems with instant feedback, plus reaction worksheets curated from the chemical literature.

US edition (27 chapters). The 4e International Adaptation differs: 28 chapters, substitution/elimination split into two chapters.

Ch	Chapter	Matching practice on RealOChem
1	A Review of General Chemistry: Electrons, Bonds, and Molecular Properties	Lewis Structures Molecular Geometry (VSEPR)
2	Molecular Representations	Determine a Molecular Formula Functional Group Identification Functional Group Classification Compare Resonance Contributors Resonance Arrows Resonance Formal Charges
3	Acids and Bases	pKa Comparison (DMSO) pKa Comparison (Water) Find the Acidic Proton Mechanism Arrows
4	Alkanes and Cycloalkanes	IUPAC Nomenclature Nomenclingo (IUPAC Name Builder) Guided IUPAC Naming Newman Projections: Identify Newman Projections: Build Newman Projections: Rotate Chair Conformations: Ring Flip Chair Conformations: Energy
5	Stereoisomerism	Assign R or S Stereochemistry Assign E or Z Stereochemistry Identify meso Compounds Stereoisomer Relationships Molecule Relationships
6	Chemical Reactivity and Mechanisms	Mechanism Arrows
7	Alkyl Halides: Nucleophilic Substitution and Elimination Reactions	SN1/SN2/E1/E2 Prediction SN1 and SN2 Reactions — literature worksheet: problems / answer key E1 and E2 Reactions — literature worksheet: problems / answer key
8	Addition Reactions of Alkenes	Electrophilic Addition to Alkenes/Alkynes — literature worksheet: problems / answer key
9	Alkynes	Electrophilic Addition to Alkenes/Alkynes — literature worksheet: problems / answer key
10	Radical Reactions	Radical Reactions — literature worksheet: problems / answer key
11	Synthesis	No practice for this chapter yet
12	Alcohols and Phenols	No practice for this chapter yet
13	Ethers and Epoxides; Thiols and Sulfides	No practice for this chapter yet
14	Infrared Spectroscopy and Mass Spectrometry	No practice for this chapter yet
15	Nuclear Magnetic Resonance Spectroscopy	No practice for this chapter yet
16	Conjugated Pi Systems and Pericyclic Reactions	Diels-Alder Reactions — literature worksheet: problems / answer key Other Pericyclic Reactions — literature worksheet: problems / answer key
17	Aromatic Compounds	Identify Aromaticity
18	Aromatic Substitution Reactions	Electrophilic Aromatic Substitution — literature worksheet: problems / answer key Nucleophilic Aromatic Substitution — literature worksheet: problems / answer key
19	Aldehydes and Ketones	Addition to Carbonyls — literature worksheet: problems / answer key Olefinations — literature worksheet: problems / answer key
20	Carboxylic Acids and Their Derivatives	Substitution at Carbonyls — literature worksheet: problems / answer key
21	Alpha Carbon Chemistry: Enols and Enolates	Keto-Enol Tautomerization — literature worksheet: problems Enolate Formation — literature worksheet: problems / answer key Enolate Alkylation — literature worksheet: problems / answer key Alpha Halogenation — literature worksheet: problems / answer key Aldol Reactions — literature worksheet: problems / answer key Claisen Condensations — literature worksheet: problems / answer key Complex Enolate Reactions — literature worksheet: problems / answer key
22	Amines	No practice for this chapter yet
23	Introduction to Organometallic Compounds	Addition to Carbonyls — literature worksheet: problems / answer key
24	Carbohydrates	No practice for this chapter yet
25	Amino Acids, Peptides, and Proteins	No practice for this chapter yet
26	Lipids	No practice for this chapter yet
27	Synthetic Polymers	No practice for this chapter yet

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