Oxidation of aldehydes to carboxylic acids
4 real reactions from the literature, on aromatic aldehydes and aliphatic aldehydes. Each scheme shows starting materials, conditions and products, with the yield and reference where the source reports them.
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Aldehyde oxidation: piperonal (an aromatic aldehyde) with KMnO4; H2O, 75 °C gives 1,3-benzodioxole-5-carboxylic acid.
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Aldehyde oxidation: vanillin (an aromatic aldehyde) with Ag2O, NaOH, H2O, 55 °C; then HCl gives vanillic acid (the carboxylic acid).
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Aldehyde oxidation: 3-thiophenecarboxaldehyde (an aromatic aldehyde) with Ag2O; NaOH, H2O gives thiophene-3-carboxylic acid.
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Aldehyde oxidation: heptanal (an aliphatic aldehyde) with KMnO4; H2SO4, H2O gives heptanoic acid (the carboxylic acid).