Lactam–lactim tautomerization

1 real reaction from the literature, on ureas. Each scheme shows starting materials, conditions and products, with the yield and reference where the source reports them.

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1. Lactam–lactim tautomerization: 1-(4-methyl-6-oxo-1H-pyrimidin-2-yl)-3-pentylurea gives 1-(4-methyl-6-oxo-1H-pyrimidin-2-yl)-3-pentylurea (the lactim tautomer).

   Lactam–lactim tautomerizationJ. Am. Chem. Soc. 2005, 127, 810